Respiratory Syncytial Virus bronchiolitis: Impact of second-hand smoke exposure on immune profiles

Respiratory Syncytial Virus bronchiolitis: Impact of second-hand smoke exposure on immune profiles

Severity of respiratory syncytial virus bronchiolitis is affected by cigarette smoke exposure and atopy.

OBJECTIVE Respiratory syncytial virus (RSV) bronchiolitis is a common cause of hospitalizations in children and has been increasingly identified as a risk factor in the development of asthma. Little is known about what determines the severity of RSV bronchiolitis, which may be helpful in the initial assessment of these children. DESIGN We evaluated a variety of environmental and host factors ...

Immunopathogenesis of respiratory syncytial virus bronchiolitis.

BACKGROUND The objective of this study was to elucidate the relation between respiratory syncytial virus (RSV) infection and cytokine/chemokine concentrations, as well as the impact that these factors have on the severity of bronchiolitis. METHODS Children <24 months old who presented to the emergency department with clinical symptoms of bronchiolitis were prospectively enrolled in the study....

Respiratory Syncytial Virus Infection and Bronchiolitis

4. Learn the epidemiologic and experimental information suggesting the existence of a link between early-life infection with RSV and the subsequent development of recurrent wheezing and asthma in childhood and adolescence. AUTHORDISCLOSUREDr Perez has disclosed no financial relationships relevant to this article. Dr Piedimonte has disclosed he receives research grant NHLBI HL-061007 from the Na...

The Effects of Second-hand Smoke Exposure on Breast Milk Cotinine and Infant Urinary Cotinine

Background & Aims: Exposure to cigarette smoke affects the health of mothers and infants. The aim of this study was to examine the effects of second-hand smoke exposure on breast milk and infant urinary cotinine during breastfeeding. Methods: This cohort study was conducted on 45 breastfeeding mothers and infants exposed to second-hand cigarette smoke (exposed group), and 40 breastfeeding mothe...